In previous blog posts I have speculated about the reasons behind the stunning drop in overdoses that have occurred in Connecticut (45% since November 2021) and nationwide (40% since August 2023). The two leading theories I subscribe to are A recent article in Science magazine, Did the illicit fentanyl trade experience a supply shock?, argued that…
Month: January 2026
Don’t Chase Wakefulness
We tell people to titrate naloxone to respirations. Just give enough to enable the person to breathe on their own. If you give them too much, you can put them into precipitated withdrawal. In other words, by knocking the opioids out of their system, you make those dependent on opioids sick. You are in terrible…

